A list of supplements that don’t work very well in the versions sold in the US
Updated October 22, 2020. Originally posted November 19, 2011. Over the years I've learned that some of the nutrient supplements on the shelves in the US don't work very well, either because a significant part of the population can't process them, or because the version used is poorly absorbed by the body, or because they are so cheaply formulated that the filler would make you sick before you could get enough of the active ingredient to resolve your deficiency. Here's everything I know so far. Needless to say, the better versions are more expensive and harder to find. Folic acid Processing this synthetic vitamin into its active form requires methyl groups and those of us who are methyl-challenged (low methylators) need to use the methylfolate version. Some sources say that…