Recently I came across a discussion forum referring to the use of niacin for social anxiety at multi-gram doses. One commenter mentioned that based on her experience, either niacin has to be repleted in much larger amounts than commonly believed, or plays a much more important role in the diet. Or both. This intrigued me. I’ve never experimented with niacin in any big way, because I never found any mention of big doses used for anything but heart disease or schizophrenia, the latter application made famous in the 60s by Dr. Abram Hoffer. Another issue was the annoying and unpredictable flushing. Somehow I had mistakenly concluded that niacinamide, a form that does not cause flushing, and no-flush niacin were the same thing, and since no-flush niacin definitely gives me flushes,…
